From 4-(2-Oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate to 2-Hydroxydec-2,4-diene-1,10-dioate

Graphic of the reaction.

Medline reference

Hernaez MJ, Floriano B, Rios JJ, Santero E. Appl Environ Microbiol (2002) 68(10): 4841-6.

Search Medline for bacterial AND tetralin AND hydrolase.

4 citations on March 09, 2012.

                           4-(2-Oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate                           
                                                  |
                                                  |  H2O
  4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate | /
                                        hydrolase |/
                                          3.7.1.- | Search GenBank, 7 hits on Apr. 03, 2012
                                                  |\
                                           ExPASy | \
                                                  |  H+
                                                  v
                                 2-Hydroxydec-2,4-diene-1,10-dioate                                  

EAWAG-BBD Biotransformation rules in accord with this reaction:

1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)

Page Author(s): Jiun-guo Yu
April 17, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1172.
It was generated on November 23, 2024 at 8:44:01 AM CST.

© 2024, EAWAG.