From (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate to (2E,4E)-2-Hydroxyhexa-2,4-dienoate and 9,17-Dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate

Graphic of the reaction.

Medline reference

Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T. Appl Environ Microbiol (2005) 71(9): 5275-81.

Search Medline for tesD AND hydrolase.

4 citations on March 09, 2012.

       (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate       
                                             |
                                             |  H2O
                                    4,9-DSHA | /
                                   hydrolase |/
                                    3.7.1.17 | Search GenBank, 5 hits on Jun. 15, 2012
                                       Kyoto |\
                                      ExPASy | \
                                             |  H+
                                             v
  (2E,4E)-2-Hydroxyhexa-2,4-dienoate + 9,17-Dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate   

EAWAG-BBD Biotransformation rules in accord with this reaction:

1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)

Page Author(s): Andrew Rabins
April 22, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1152.
It was generated on November 7, 2025 at 3:28:01 PM CST.

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