From Androsta-1,4-diene-3,17-dione to 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

Graphic of the reaction.

Medline reference

Horinouchi M, Hayashi T, Yamamoto T, Kudo T. Appl Environ Microbiol (2003) 69(8): 4421-30.

Search Medline for 3-ketosteroid 9alpha-hydroxylase.

13 citations on June 21, 2012.

               Androsta-1,4-diene-3,17-dione                
                              |
                              |  reduced ferredoxin + O2
                3-ketosteroid | /
           9alpha-hydroxylase |/
                  1.14.13.142 | Search GenBank, 29 hits on Jun. 20, 2012
                        Kyoto |\
                       ExPASy | \
                              |  H2O + oxidized ferredoxin
                              v
       [9alpha-Hydroxy-1,4-androstadiene-3,17-dione]        
                              |
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                              v
  3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione   

Page Author(s): Andrew Rabins
April 22, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1149.
It was generated on March 22, 2025 at 9:20:45 PM CDT.

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