From Hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid to Hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid

Graphic of the reaction.
Medline reference: Fillgrove KL, Pakhomova S, Newcomer ME, Armstrong RN. J Am Chem Soc (2003) 125(51): 15730-1.
Search Medline titles for fosfomycin resistance AND mechanistic.: 8 citations on March 09, 2012.

      Hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid       
                                |
                                |  Glutathione
                    glutathione | /
                    transferase |/
                       2.5.1.18 | Search GenBank, 591 hits on Apr. 03, 2012
                          Kyoto |
                         ExPASy |
                                |
                                v
  Hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid

Display a pathway starting from this reaction.

[Fosfomycin] [BBD Main Menu]

Page Author(s): David Joseph De Grio
November 13, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r1073.
It was generated on November 23, 2024 at 3:28:01 AM CST.

© 2024, EAWAG.