From Dimethylmalonate to Isobutyrate

Graphic of the reaction.

Medline reference
Probian C, Wulfing A, Harder J. Appl Environ Microbiol (2003) 69(3): 1866-70.

Search Medline for Pivalic Acid AND Bacteria.
9 citations on March 09, 2012. 
           Dimethylmalonate            
                   |
                   |  H+
  dimethylmalonate | /
     decarboxylase |/
           4.1.1.- |
                   |\
            ExPASy | \
                   |  CO2
                   v
              Isobutyrate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2- or 3- substituted Carboxylate -----> RH + CO2 (bt0051)
[Pivalic Acid (anaerobic)] [BBD Main Menu]

Page Author(s): Matthew Smith
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r1031.
It was generated on January 20, 2026 at 12:09:18 AM CST. 

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