From 3,5-Dichloro-3-methyl-cis,cis-muconate to 2-Chloro-5-methyl-cis-dienelactone

Graphic of the reaction.
Medline reference: Pollmann K, Kaschabek S, Wray V, Reineke W, Pieper DH. J Bacteriol (2002) 184(19): 5261-74.
Search Medline for chloromuconate cycloisomerase.: 36 citations on March 09, 2012.

  3,5-Dichloro-3-methyl-cis,cis-muconate   
                     |
                     |
      chloromuconate |
      cycloisomerase |
             5.5.1.7 | Search GenBank, 227 hits on Apr. 03, 2012
               Kyoto |\
              ExPASy | \
                     |  Cl^-
                     v
    2-Chloro-5-methyl-cis-dienelactone

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)

[2,4-Dichlorotoluene] [BBD Main Menu]

Page Author(s): David Wunder
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0960.
It was generated on February 17, 2026 1:51:40 AM CST.

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