From Pyrene to cis-4,5-Dihydroxy-4,5-dihydropyrene

Graphic of the reaction.

Medline reference
Rehmann K, Noll HP, Steinberg CE, Kettrup AA. Chemosphere (1998) 36(14): 2977-92.

Search Medline for 4,5-Dihydroxy-4,5-dihydropyrene.
3 citations on August 21, 2012. 
                 Pyrene                 
                    |
                    |  2H+ + 2e- + O2
             pyrene | /
        dioxygenase |/
          1.14.12.- |
                    |
             ExPASy |
                    |
                    v
  cis-4,5-Dihydroxy-4,5-dihydropyrene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydrodihydroxyaromatic (bt0367)
[Pyrene] [BBD Main Menu]

Page Author(s): Nathaniel Keith
October 18, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0934.
It was generated on May 12, 2026 at 7:11:23 AM CDT. 

© 2026, EAWAG.