From 2,2-bis(4-Hydroxyphenyl)-1-propanol to 2,3-bis(4-Hydroxyphenyl)-1,2-propanediol

Graphic of the reaction.
Graphic of its mechanism.
Medline reference: Spivack J, Leib TK, Lobos JH. J Biol Chem (1994) 269(10): 7323-9.

                     2,2-bis(4-Hydroxyphenyl)-1-propanol                     
                                      |
                                      |  NADH + H⁺ + O₂
  2,2-bis(4-hydroxyphenyl)-1-propanol | /
                          hydroxylase |/
                            1.14.13.- |
                                      |\
                               ExPASy | \
                                      |  NAD⁺ + H₂O
                                      v
                  2,3-bis(4-Hydroxyphenyl)-1,2-propanediol

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: Bisphenol A derivative -----> 1,2-bis(4-Hydroxyphenyl)-2-propanol derivative (bt0225)

[Bisphenol A] [BBD Main Menu]

Page Author(s): Prasad Kotharu
November 12, 2002 Contact Us

This is the EAWAG-BBD reaction, reacID# r0864.
It was generated on February 1, 2025 at 12:05:57 AM CST.

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