From Bisphenol A to 2,2-bis(4-Hydroxyphenyl)-1-propanol

Graphic of the reaction.

Graphic of its mechanism.

Medline reference
Spivack J, Leib TK, Lobos JH. J Biol Chem (1994) 269(10): 7323-9.

Search Medline titles for bisphenol A[ti] AND 2,2-bis(4-Hydroxyphenyl)-1-propanol.
5 citations on August 21, 2012. 
                     Bisphenol A                     
                          |
                          |  NADH + H+ + O2
  bisphenol A hydroxylase | /
                        A |/
                1.14.13.- |
                          |\
                   ExPASy | \
                          |  NAD+ + H2O
                          v
                   [Phenonium ion]                   
                          |
                          |
                          |
                          |
                          |
                          |
                          |
                          v
         2,2-bis(4-Hydroxyphenyl)-1-propanol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
aliphatic Methyl [H0] -----> primary Alcohol (bt0332)
[Bisphenol A] [BBD Main Menu]

Page Author(s): Prasad Kotharu
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0861.
It was generated on December 12, 2025 at 12:52:14 AM CST. 

© 2025, EAWAG.