From (R)-2-Hydroxypropyl-CoM to 2-Oxopropyl-CoM

Graphic of the reaction.

Medline reference

Allen JR, Clark DD, Krum JG, Ensign SA. Proc Natl Acad Sci U S A (1999) 96(15): 8432-7.

Search Medline for 2-hydroxypropyl AND "Coenzyme M" AND bacteria.

10 citations on March 09, 2012.

                    (R)-2-Hydroxypropyl-CoM                    
                               |
                               |  NAD+
         2-R-hydroxypropyl-CoM | /
                 dehydrogenase |/
                     1.1.1.268 | Search GenBank, 22 hits on Apr. 03, 2012
                         Kyoto |\
                        ExPASy | \
                               |  NADH + H+
                               v
                        2-Oxopropyl-CoM                        

EAWAG-BBD Biotransformation rules in accord with this reaction:

secondary Alcohol -----> Ketone (bt0002)

Page Author(s): Prasad Kotharu
November 12, 2002 Contact Us

This is the EAWAG-BBD reaction, reacID# r0852.
It was generated on January 20, 2026 at 2:12:01 AM CST.

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