From 1,4-Dichlorobenzene to 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene

Graphic of the reaction.

Medline reference
Spiess E, Sommer C, Gorisch H. Appl Environ Microbiol (1995) 61(11): 3884-8.

Search Medline for chlorobenzene dioxygenase.
18 citations on March 09, 2012. 
                 1,4-Dichlorobenzene                  
                           |
                           |  O2 + NADH + H+
             chlorobenzene | /
               dioxygenase |/
                 1.14.12.- | Search GenBank, 10 hits on Apr. 03, 2012
                           |\
                    ExPASy | \
                           |  NAD+
                           v
  3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydrodihydroxyaromatic (bt0367)
[1,4-Dichlorobenzene] [BBD Main Menu]

Page Author(s): Jiangbi Liu
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0653.
It was generated on November 7, 2025 at 3:18:31 PM CST. 

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