From 2-Hydroxy-2-methyl-1,3-dicarbonate to L-Lactate

Graphic of the reaction.

Medline reference
Steffan RJ, McClay K, Vainberg S, Condee CW, Zhang D. Appl Environ Microbiol (1997) 63(11): 4216-22.

Search Medline for 2-Hydroxyisobutyrate AND bacteria.
10 citations on August 16, 2012. 
                    2-Hydroxy-2-methyl-1,3-dicarbonate                     
                                     |
                                     |  H+
  2-hydroxy-2-methyl-1,3-dicarbonate | /
                       decarboxylase |/
                             4.1.1.- |
                                     |\
                              ExPASy | \
                                     |  CO2
                                     v
                                 L-Lactate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2- or 3- substituted Carboxylate -----> RH + CO2 (bt0051)
[Methyl tert-butyl ether] [BBD Main Menu]

Page Author(s): Charlotte Rosendahl Pedersen
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0621.
It was generated on January 20, 2026 at 3:08:35 AM CST. 

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