From 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)hexa-2,4-dienoate to Catechol and 2-Hydroxymuconate

Graphic of the reaction.

Medline reference
Wittich RM, Wilkes H, Sinnwell V, Francke W, Fortnagel P. Appl Environ Microbiol (1992) 58(3): 1005-10.

Search Medline for 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate AND hydrolase.
25 citations on March 09, 2012. 
                              2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)hexa-2,4-dienoate                              
                                                        |
                                                        |  H2O
  2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)hexa-2,4-dienoate | /
                                               esterase |/
                                                3.1.1.- |
                                                        |\
                                                 ExPASy | \
                                                        |  H+
                                                        v
                                          Catechol + 2-Hydroxymuconate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Ester -----> Alcohol + Carboxylate (bt0024)
[Dibenzo-p-dioxin] [BBD Main Menu]

Page Author(s): Greg S. Bill
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0573.
It was generated on April 15, 2026 at 3:09:49 PM CDT. 

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