From 2,5-Dichloro-4-oxohex-2-enedioate to 2-Chloro-3-oxoadipate

Graphic of the reaction.
Medline reference: Kasberg T, Daubaras DL, Chakrabarty AM, Kinzelt D, Reineke W. J Bacteriol (1995) 177(13): 3885-9.
Search Medline titles for maleylacetate reductase.: 16 citations on August 16, 2012.

  2,5-Dichloro-4-oxohex-2-enedioate   
                   |
                   |  2NADH + H⁺
     maleylacetate | /
         reductase |/
          1.3.1.32 | Search GenBank, 225 hits on Apr. 03, 2012
             Kyoto |\
            ExPASy | \
                   |  2NAD⁺ + Cl^-
                   v
        2-Chloro-3-oxoadipate

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 2-Halomaleylacetate -----> 3-Oxoadipate derivative (bt0149)

[1,2,4-Trichlorobenzene (an/aerobic)] [BBD Main Menu]

Page Author(s): Guang Yao
February 10, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r0531.
It was generated on November 11, 2025 at 5:12:55 PM CST.

© 2025, EAWAG.