From 2,3,5-Trichloro-cis,cis-muconate to 2,5-Dichloro-carboxymethylenebut-2-en-4-olide

Graphic of the reaction.
Medline reference: van der Meer JR, van Neerven AR, de Vries EJ, de Vos WM, Zehnder AJ. J Bacteriol (1991) 173(1): 6-15.
Search Medline for 1,2,4-trichlorobenzene and cycloisomerase II.: 1 citations on March 09, 2012.

         2,3,5-Trichloro-cis,cis-muconate         
                         |
                         |
          chloromuconate |
          cycloisomerase |
                 5.5.1.7 | Search GenBank, 227 hits on Apr. 03, 2012
                   Kyoto |\
                  ExPASy | \
                         |  Cl^-
                         v
  2,5-Dichloro-carboxymethylenebut-2-en-4-olide

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)

[1,2,4-Trichlorobenzene (an/aerobic)] [BBD Main Menu]

Page Author(s): Guang Yao
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0529.
It was generated on December 4, 2025 at 6:25:30 PM CST.

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