From 1,2,4-Trichlorobenzene to 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene

Graphic of the reaction.

Medline reference
van der Meer JR, van Neerven AR, de Vries EJ, de Vos WM, Zehnder AJ. J Bacteriol (1991) 173(1): 6-15.

Search Medline for 1,2,4-trichlorobenzene and dioxygenase.
13 citations on March 09, 2012. 
                 1,2,4-Trichlorobenzene                  
                            |
                            |  NADH + H+ + O2
              chlorobenzene | /
                dioxygenase |/
                  1.14.12.- | Search GenBank, 10 hits on Apr. 03, 2012
                            |\
                     ExPASy | \
                            |  NAD+
                            v
  3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydrodihydroxyaromatic (bt0367)
[1,2,4-Trichlorobenzene (an/aerobic)] [BBD Main Menu]

Page Author(s): Guang Yao
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0526.
It was generated on November 16, 2025 at 3:28:33 PM CST. 

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