From 4-Hydroxylamino-2,6-dinitrotoluene to 4-Amino-2,6-dinitrotoluene

Graphic of the reaction.

Medline reference
Vorbeck C, Lenke H, Fischer P, Spain JC, Knackmuss HJ. Appl Environ Microbiol (1998) 64(1): 246-252.

Search Medline for 4-amino-2,6-dinitrotoluene and bacteria.
16 citations on March 09, 2012. 
  4-Hydroxylamino-2,6-dinitrotoluene   
                   |
                   |  NAD(P)H + H+
           NAD(P)H | /
    nitroreductase |/
           1.7.1.- | Search GenBank, 256 hits on Apr. 03, 2012
                   |\
            ExPASy | \
                   |  NAD(P)+ + H2O
                   v
      4-Amino-2,6-dinitrotoluene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
aromatic Hydroxylamine -----> aromatic Amine (bt0035)
[Trinitrotoluene] [2,4,6-Trinitrotoluene (anaerobic)] [BBD Main Menu]

Page Author(s): Sara McFarlan
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0500.
It was generated on December 12, 2025 at 12:29:23 AM CST. 

© 2025, EAWAG.