From 2,4,6-Trinitrotoluene to 2-Amino-4,6-dinitrotoluene

Graphic of the reaction.

Medline reference
Martin JL, Comfort SD, Shea PJ, Kokjohn TA, Drijber RA. Can J Microbiol (1997) 43(5): 447-55.

Search Medline for trinitrotoluene AND nitroreductase.
40 citations on March 09, 2012. 

       2,4,6-Trinitrotoluene       
                 |
                 |  3NAD(P)H + 3H+
         NAD(P)H | /
  nitroreductase |/
         1.7.1.- | Search GenBank, 256 hits on Apr. 03, 2012
                 |\
          ExPASy | \
                 |  3NAD(P)+ + 2H2O
                 v
    2-Amino-4,6-dinitrotoluene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Nitroaromatic -----> Aminoaromatic (bt0080)
[Trinitrotoluene] [2,4,6-Trinitrotoluene (anaerobic)] [BBD Main Menu]

Page Author(s): Sara McFarlan
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0476.
It was generated on November 14, 2025 at 2:14:28 PM CST. 

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