From 2,4-Dihydroxylamino-6-nitrotoluene to 4-Amino-2-hydroxylamino-6-nitrotoluene

Graphic of the reaction.

Medline reference

Fiorella PD, Spain JC. Appl Environ Microbiol (1997) 63(5): 2007-2015.

Search Medline for nitroreductase AND nitrotoluene.

6 citations on March 09, 2012.

    2,4-Dihydroxylamino-6-nitrotoluene     
                     |
                     |  NAD(P)H + H+
             NAD(P)H | /
      nitroreductase |/
             1.7.1.- | Search GenBank, 256 hits on Apr. 03, 2012
                     |\
              ExPASy | \
                     |  NAD(P)+ + H2O
                     v
  4-Amino-2-hydroxylamino-6-nitrotoluene   

EAWAG-BBD Biotransformation rules in accord with this reaction:

aromatic Hydroxylamine -----> aromatic Amine (bt0035)

Page Author(s): Sara McFarlan
December 31, 2001 Contact Us

This is the EAWAG-BBD reaction, reacID# r0467.
It was generated on March 11, 2026 at 8:34:07 AM CDT.

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