From Methionine to Methanethiol and 2-Oxobutanoate

Graphic of the reaction.

Graphic of its mechanism.

Medline reference
Johnston M, Jankowski D, Marcotte P, Tanaka H, Esaki N, Soda K, Walsh C. Biochemistry (1979) 18(21): 4690-701.

Search Medline titles for bacterial methionine gamma-lyase.
42 citations on August 07, 2012. 
              Methionine               
                   |
                   |
  methionine gamma |
             lyase |
          4.4.1.11 | Search GenBank, 1224 hits on Apr. 03, 2012
             Kyoto |
            ExPASy |
                   |
                   v
        [2-Ammoniobut-2-enoate]        
                   |
                   |  H2O
                   | /
                   |/
                   |
                   |\
                   | \
                   |  NH4+
                   v
     Methanethiol + 2-Oxobutanoate
Display a pathway starting from this reaction.

[Methionine and Threonine] [BBD Main Menu]

Page Author(s): Hugh McTavish and Zhifu Sun
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0432.
It was generated on December 15, 2025 at 9:39:43 PM CST. 

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