From cis-5-Carboxymethyl-2-oxohex-3-ene-1,6-dioate to cis-2-Oxohept-3-ene-1,7-dioate

Graphic of the reaction.

Medline reference
Roper DI, Cooper RA. Eur J Biochem (1993) 217(2): 575-80.

Search Medline for homoprotocatechuate decarboxylase.
3 citations on March 09, 2012. 
                 cis-5-Carboxymethyl-2-oxohex-3-ene-1,6-dioate                 
                                       |
                                       |  H+
  5-oxopent-3-ene-1,2,5-tricarboxylate | /
                         decarboxylase |/
                              4.1.1.68 | Search GenBank, 481 hits on Apr. 03, 2012
                                 Kyoto |\
                                ExPASy | \
                                       |  CO2
                                       v
               [2-Hydroxyhepta-trans,trans-2,4-diene-1,7-dioate]               
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                                       v
                        cis-2-Oxohept-3-ene-1,7-dioate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2- or 3- substituted Carboxylate -----> RH + CO2 (bt0051)
[Tyrosine] [BBD Main Menu]

Page Author(s): Colin L. Sweeney and Michael Turnbull
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0367.
It was generated on November 11, 2025 at 4:41:09 AM CST. 

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