From 3,4-Dihydroxyphenylacetate to trans,cis-5-Carboxymethyl-2-hydroxymuconate semialdehyde

Graphic of the reaction.

Medline reference
Roper DI, Fawcett T, Cooper RA. Mol Gen Genet (1993) 237(1-2): 241-50.

Search Medline for 3,4-dihydroxyphenylacetate 2,3-dioxygenase.
45 citations on August 02, 2012. 
                 3,4-Dihydroxyphenylacetate                  
                              |
                              |  O2
   3,4-dihydroxyphenylacetate | /
              2,3-dioxygenase |/
                   1.13.11.15 | Search GenBank, 326 hits on Apr. 03, 2012
                        Kyoto |
                       ExPASy |
                              |
                              v
  trans,cis-5-Carboxymethyl-2-hydroxymuconate semialdehyde
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)
[Tyrosine] [BBD Main Menu]

Page Author(s): Michelle Wagner and Colin L. Sweeney
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0364.
It was generated on November 13, 2025 at 3:08:12 PM CST. 

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