From 2,6-Dichlorohydroquinone (DiCH) to 2-Chloromaleylacetate

Graphic of the reaction.

Medline reference
Xun L, Bohuslavek J, Cai M. Biochem Biophys Res Commun (1999) 266(2): 322-5.

Search Medline for 2,6-dichlorohydroquinone 1,2-dioxygenase.
3 citations on July 26, 2012. 
               2,6-Dichlorohydroquinone (DiCH)               
                              |
                              |  O2
  2,6-dichloro-p-hydroquinone | /
              1,2-dioxygenase |/
                    1.13.11.- | Search GenBank, 2 hits on Apr. 03, 2012
                              |\
                       ExPASy | \
                              |  H+
                              v
    [(2E,4E)-1,5-Dichloro-3-hydroxy-muconic semialdehyde]    
                              |
                              |  H2O
                              | /
                              |/
                              |
                              |\
                              | \
                              |  2H+ + Cl-
                              v
                    2-Chloromaleylacetate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1,4-Dihydroxy-2-halobenzenoid -----> 2-Halomaleylacetate (bt0069)
[Pentachlorophenol Family] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0319.
It was generated on November 16, 2025 at 4:29:49 PM CST. 

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