From 4-Chlorophenylacetate to 3,4-Dihydroxyphenylacetate

Graphic of the reaction.

Medline reference
Schweizer D, Markus A, Seez M, Ruf HH, Lingens F. J Biol Chem (1987) 262(19): 9340-6.

Search Medline for chlorophenylacetate dioxygenase.
3 citations on March 09, 2012. 
              4-Chlorophenylacetate              
                        |
                        |  NADH + H+ + O2
  4-chlorophenylacetate | /
        3,4-dioxygenase |/
              1.14.12.9 |
                  Kyoto |\
                 ExPASy | \
                        |  NAD+ + HCl
                        v
           3,4-Dihydroxyphenylacetate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
4-Halophenylacetate derivative -----> 3,4-Dihydroxyphenylacetate derivative (bt0366)
[Tyrosine] [BBD Main Menu]

Page Author(s): Karl J Clark and Zhifu Sun
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0308.
It was generated on March 11, 2026 at 5:31:52 AM CDT. 

© 2026, EAWAG.