From 4-Hydroxyphenylacetate to Homogentisate

Graphic of the reaction.

Medline reference
Hareland WA, Crawford RL, Chapman PJ, Dagley S. J Bacteriol (1975) 121(1): 272-85.

Search Medline for 4-hydroxyphenylacetate 1-hydroxylase.
1 citations on March 09, 2012. 

              4-Hydroxyphenylacetate               
                         |
                         |  NADH + O2
  4-hydroxyphenylacetate | /
           1-hydroxylase |/
              1.14.13.18 |
                   Kyoto |\
                  ExPASy | \
                         |  NAD+ + OH-
                         v
                   Homogentisate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2,5-unsubstituted 4-Hydroxyphenylacetate derivative -----> 2,5-Dihydroxyphenylacetate derivative (bt0234)
[Tyrosine] [BBD Main Menu]

Page Author(s): Colin L. Sweeney
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0300.
It was generated on April 15, 2026 at 3:03:36 PM CDT. 

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