From Toluene to 4-Hydroxytoluene

Graphic of the reaction.

Medline reference

Yen KM, Karl MR, Blatt LM, Simon MJ, Winter RB, Fausset PR, Lu HS, Harcourt AA, Chen KK. J Bacteriol (1991) 173(17): 5315-27.

Search Medline for toluene 4-monooxygenase.

65 citations on March 09, 2012.

               Toluene               
                  |
                  |  NADH + H+ + O2
          toluene | /
  4-monooxygenase |/
        1.14.13.- | Search GenBank, 59 hits on Apr. 03, 2012
                  |\
           ExPASy | \
                  |  NAD+ + H2O
                  v
          4-Hydroxytoluene           

EAWAG-BBD Biotransformation rules in accord with this reaction:

monosubstituted Benzenoid -----> Add p-OH (bt0013)

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0255.
It was generated on April 11, 2026 at 12:45:10 AM CDT.

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