From Acetophenone to 2-Hydroxyacetophenone

Graphic of the reaction.

Medline reference
Lee K, Gibson DT. Appl Environ Microbiol (1996) 62(9): 3101-6.

Search Medline titles for naphthalene dioxygenase.
55 citations on March 09, 2012.

Reactions of naphthalene 1,2-dioxygenase 
            Acetophenone             
                  |
                  |  NADH + H+ + O2
      naphthalene | /
  1,2-dioxygenase |/
       1.14.12.12 | Search GenBank, 95 hits on Apr. 03, 2012
            Kyoto |\
           ExPASy | \
                  |  NAD+ + H2O
                  v
        2-Hydroxyacetophenone
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
aliphatic Methyl [H0] -----> primary Alcohol (bt0332)
[Ethylbenzene] [BBD Main Menu]

Page Author(s): Ryan McLeish
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0251.
It was generated on November 12, 2025 at 2:03:39 PM CST. 

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