From o-Methylbenzoate to 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate

Graphic of the reaction.

Medline reference
Higson FK, Focht DD. Appl Environ Microbiol (1992) 58(1): 194-200.

Search Medline titles for toluate dioxygenase.
8 citations on March 09, 2012. 
                    o-Methylbenzoate                     
                            |
                            |  NADH + O2 + H+
                    toluate | /
                dioxygenase |/
                  1.14.12.- |
                            |\
                     ExPASy | \
                            |  NAD+
                            v
  1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[o-Xylene] [BBD Main Menu]

Page Author(s): Dong Jun Oh
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0223.
It was generated on November 11, 2025 at 5:34:54 AM CST. 

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