From m-Methylbenzoate to 1,2-Dihydroxy-3-methylcyclohexa-3,5-dienecarboxylate

Graphic of the reaction.

Medline reference
Harayama S, Rekik M, Timmis KN. Mol Gen Genet (1986) 202(2): 226-34.

Search Medline titles for toluate dioxygenase.
8 citations on March 09, 2012. 
                    m-Methylbenzoate                     
                            |
                            |  NADH + O2 + H+
                    toluate | /
                dioxygenase |/
                  1.14.12.- |
                            |\
                     ExPASy | \
                            |  NAD+
                            v
  1,2-Dihydroxy-3-methylcyclohexa-3,5-dienecarboxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[m-Xylene] [BBD Main Menu]

Page Author(s): Brian A. Hyatt and Dong Jun Oh
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0215.
It was generated on June 17, 2026 at 8:14:04 PM CDT. 

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