From 4-Methylcatechol to 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde

Graphic of the reaction.
Medline reference: Cerdan P, Wasserfallen A, Rekik M, Timmis KN, Harayama S. J Bacteriol (1994) 176(19): 6074-81.
Search Medline titles for catechol 2,3-dioxygenase AND 4-methylcatechol.: 11 citations on March 09, 2012.

                  4-Methylcatechol                  
                          |
                          |  O₂
                 catechol | /
          2,3-dioxygenase |/
                1.13.11.2 | Search GenBank, 925 hits on Apr. 03, 2012
                    Kyoto |
                   ExPASy |
                          |
                          v
  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)

[p-Xylene] [BBD Main Menu]

Page Author(s): Stephen Stephens
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0180.
It was generated on April 11, 2026 at 12:10:03 AM CDT.

© 2026, EAWAG.