From 2,3-Dihydroxy-4'-chlorobiphenyl to 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate

Graphic of the reaction.

Medline reference
Eltis LD, Hofmann B, Hecht HJ, Lunsdorf H, Timmis KN. J Biol Chem (1993) 268(4): 2727-32.

Search Medline titles for 2,3-dihydroxybiphenyl 1,2-dioxygenase.
24 citations on May 30, 2012. 
             2,3-Dihydroxy-4'-chlorobiphenyl              
                             |
                             |  O2
       2,3-dihydroxybiphenyl | /
             1,2-dioxygenase |/
                  1.13.11.39 | Search GenBank, 135 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  H+
                             v
  2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)
[4-Chlorobiphenyl] [BBD Main Menu]

Page Author(s): Shou-Lin Chang and Dong Jun Oh
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0135.
It was generated on November 16, 2025 at 9:59:39 AM CST. 

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