From Chlorobenzene to 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene

Graphic of the reaction.

Medline reference
Werlen C, Kohler HP, van der Meer JR. J Biol Chem (1996) 271(8): 4009-16.

Search Medline for chlorobenzene dioxygenase.
18 citations on June 12, 2012. 
                  Chlorobenzene                   
                         |
                         |  O2 + NADH + H+
           chlorobenzene | /
             dioxygenase |/
               1.14.12.- | Search GenBank, 10 hits on Apr. 03, 2012
                         |\
                  ExPASy | \
                         |  NAD+
                         v
  3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
mono-halo-substituted Benzenoid -----> 1-halo-2,3-dihydrodihydroxy Benzenoid (bt0369)
[Chlorobenzene] [BBD Main Menu]

Page Author(s): Ryan McLeish
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0097.
It was generated on January 18, 2026 at 8:24:54 PM CST. 

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