The EAWAG-BBD Testosterone Pathway

• Androst-4-ene-3,17-dione -----> Androsta-1,4-diene-3,17-dione (reacID# r1148)
• Androst-4-ene-3,17-dione -----> 9α-Hydroxy-4-androstene-3,17-dione (reacID# r1153)
• Androsta-1,4-diene-3,17-dione -----> 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (reacID# r1149)
• 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione -----> (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate (reacID# r1151)
• 9,17-Dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate -----> Carbon Dioxide (reacID# r1298)
• (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate -----> 9,17-Dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2E,4E)-2-Hydroxyhexa-2,4-dienoate (reacID# r1152)
• 9α-Hydroxy-4-androstene-3,17-dione -----> 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (reacID# r1154)
• 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione -----> 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (reacID# r1150)
• 17beta-Hydroxyandrosta-1,4-diene-3-one -----> Androsta-1,4-diene-3,17-dione (reacID# r1285)
• (2E,4E)-2-Hydroxyhexa-2,4-dienoate -----> 4-Hydroxy-2-oxohexanoate (reacID# r1281)
• Testosterone -----> Androst-4-ene-3,17-dione (reacID# r1147)
• Testosterone -----> 17beta-Hydroxyandrosta-1,4-diene-3-one (reacID# r1284)

• Androst-4-ene-3,17-dione [63-05-8] (compID# c1015)
• Androsta-1,4-diene-3,17-dione [897-06-3] (compID# c1016)
• Carbon Dioxide [124-38-9] (compID# c0131)
• 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (compID# c1122)
• 9,17-Dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate (compID# c1028)
• (3E,1Z)-4,5-9,10-Diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate (compID# c1024)
• 4-Hydroxy-2-oxohexanoate (compID# c0206)
• 9α-Hydroxy-4-androstene-3,17-dione (compID# c1030)
• 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (compID# c1121)
• 17beta-Hydroxyandrosta-1,4-diene-3-one [846-48-0] (compID# c1125)
• (2E,4E)-2-Hydroxyhexa-2,4-dienoate (compID# c1027)
• Testosterone [58-22-0] (compID# c1014)

• EC 1.1.1.51 beta-hydroxysteroid dehydrogenase (enzymeID# e0711)
• EC 1.3.99.4 3-ketosteroid-delta1-dehydrogenase (enzymeID# e0712)
• EC 1.13.11.25 3,4-DHSA 4,5-dioxygenase (enzymeID# e0715)
• EC 1.14.13.142 3-ketosteroid 9alpha-hydroxylase (enzymeID# e0713)
• EC 1.14.14.12 3-HSA hydroxylase (enzymeID# e0714)
• EC 1.14.15.- 4-AD 9alpha-hydroxylase (enzymeID# e0807)
• EC 3.7.1.17 4,9-DSHA hydrolase (enzymeID# e0716)
• EC 4.2.1.132 2-hydroxyhexa-2,4-dienoate hydratase (enzymeID# e0809)

Page Author(s): Andrew W. Rabins and Carla Essenberg
Sun Feb 19 13:52:43 CST 2006 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Testosterone Pathway.
It was generated on February 16, 2026 5:18:42 AM CST.

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