The EAWAG-BBD n-Hexane (anaerobic) Pathway

• n-Hexane + Fumarate -----> (1-Methylpentyl)succinate (reacID# r0920)
• 3-Hydroxy-2-methylhexanoyl-CoA -----> 2-Methyl-3-oxohexanoyl-CoA (reacID# r0930)
• 3-Hydroxy-4-methyloctanoyl-CoA -----> 4-Methyl-3-oxooctanoyl-CoA (reacID# r0926)
• 2-Methyl-3-oxohexanoyl-CoA -----> Butyryl-CoA + Propanoyl-CoA (reacID# r0931)
• 4-Methyl-3-oxooctanoyl-CoA -----> Acetyl-CoA + 2-Methylhexanoyl-CoA (reacID# r0927)
• 2-Methylhex-2-enoyl-CoA -----> 3-Hydroxy-2-methylhexanoyl-CoA (reacID# r0929)
• 2-Methylhexanoyl-CoA -----> 2-Methylhex-2-enoyl-CoA (reacID# r0928)
• (2-Methylhexyl)malonyl-CoA + Pyruvate -----> Oxaloacetate + 4-Methyloctanoyl-CoA (reacID# r0923)
• 4-Methyloct-2-enoyl-CoA -----> 3-Hydroxy-4-methyloctanoyl-CoA (reacID# r0925)
• 4-Methyloctanoyl-CoA -----> 4-Methyloct-2-enoyl-CoA (reacID# r0924)
• (1-Methylpentyl)succinate -----> (1-Methylpentyl)succinyl-CoA (reacID# r0921)
• (1-Methylpentyl)succinyl-CoA -----> (2-Methylhexyl)malonyl-CoA (reacID# r0922)

• Acetyl-CoA [72-89-9] (compID# c0031)
• Butyryl-CoA [2140-48-9] (compID# c0023)
• Fumarate [110-17-8] (compID# c0111)
• n-Hexane [110-54-3] (compID# c0829)
• 3-Hydroxy-2-methylhexanoyl-CoA (compID# c0839)
• 3-Hydroxy-4-methyloctanoyl-CoA (compID# c0835)
• 2-Methyl-3-oxohexanoyl-CoA (compID# c0840)
• 4-Methyl-3-oxooctanoyl-CoA (compID# c0836)
• 2-Methylhex-2-enoyl-CoA (compID# c0838)
• 2-Methylhexanoyl-CoA (compID# c0837)
• (2-Methylhexyl)malonyl-CoA (compID# c0832)
• 4-Methyloct-2-enoyl-CoA (compID# c0834)
• 4-Methyloctanoyl-CoA (compID# c0833)
• (1-Methylpentyl)succinate (compID# c0830)
• (1-Methylpentyl)succinyl-CoA (compID# c0831)
• Oxaloacetate [328-42-7] (compID# c1475)
• Propanoyl-CoA [317-66-8] (compID# c0363)
• Pyruvate [127-17-3] (compID# c0159)

• EC 1.1.-.- 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase (enzymeID# e0583)
• EC 1.1.-.- 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase (enzymeID# e0579)
• EC 1.3.-.- 4-methyloctanoyl-CoA dehydrogenase (enzymeID# e0577)
• EC 1.3.99.- 2-methylhexanoyl-CoA dehydrogenase (enzymeID# e0581)
• EC 2.1.3.1 methylmalonyl-CoA carboxyltransferase (enzymeID# e0576)
• EC 2.3.1.- butyryl-CoA 2-C-propionyltransferase (enzymeID# e0584)
• EC 2.3.1.- 2-methylhexanoyl-CoA C-acetyltransferase (enzymeID# e0580)
• EC 2.8.3.5 succinyl-CoA transferase (enzymeID# e0574)
• EC 4.1.99.- (1-methylpentyl)succinate synthase (enzymeID# e0573)
• EC 4.2.1.- 4-methyloct-2-enoyl-CoA hydratase (enzymeID# e0578)
• EC 4.2.1.- 2-methylhex-2-enoyl-CoA hydratase (enzymeID# e0582)
• EC 5.4.99.2 methylmalonyl-CoA mutase (enzymeID# e0575)

Page Author(s): Gang Cheng
Thu Nov 1 14:19:06 CDT 2007 Contact Us

This is the EAWAG-BBD compounds and reactions page for the n-Hexane (anaerobic) Pathway.
It was generated on November 16, 2025 at 3:35:30 PM CST.

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