The EAWAG-BBD Dibenzothiophene Degradation Pathway

• Dibenzothiophene -----> cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene (reacID# r0160)
• cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene -----> 1,2-Dihydroxydibenzothiophene (reacID# r0161)
• 1,2-Dihydroxydibenzothiophene -----> cis-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate (reacID# r0162)
• cis-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate -----> trans-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate (reacID# r0163)
• trans-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate -----> 3-Hydroxy-2-formylbenzothiophene + Pyruvate (reacID# r0164)
• 3-Hydroxy-2-formylbenzothiophene -----> Carbon Dioxide (reacID# r0505)

• Carbon Dioxide [124-38-9] (compID# c0131)
• Dibenzothiophene [132-65-0] (compID# c0118)
• cis-1,2-Dihydroxy-1,2-dihydrodibenzothiophene (compID# c0133)
• 1,2-Dihydroxydibenzothiophene (compID# c0196)
• cis-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate (compID# c0197)
• trans-4-[2-(3-Hydroxy)-thionaphthenyl]-2-oxo-3-butenoate (compID# c0198)
• 3-Hydroxy-2-formylbenzothiophene [27751-82-2] (compID# c0199)
• Pyruvate [127-17-3] (compID# c0159)

• EC 1.3.1.29 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase (enzymeID# e0122)
• EC 1.13.11.56 1,2-dihydroxynaphthalene dioxygenase (enzymeID# e0255)
• EC 1.14.12.12 naphthalene 1,2-dioxygenase (enzymeID# e0002)
• EC 4.1.2.25 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (enzymeID# e0257)
• EC 5.99.1.4 2-hydroxychromene-2-carboxylate isomerase (enzymeID# e0163)

Page Author(s): Gulin Oz and Dong Jun Oh
December 15, 1997 4:42:21 PM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the Dibenzothiophene Degradation Pathway.
It was generated on January 17, 2026 at 10:22:43 PM CST.

© 2026, EAWAG.