The EAWAG-BBD Thiophene-2-carboxylate Pathway

• (2Z)-5-Carboxy-2-sulfanylpent-2-enoyl-CoA -----> 2-Oxoglutaryl-CoA (reacID# r1237)
• 5-Oxo-4,5-dihydrothiophene-2-carboxyl-CoA -----> (2Z)-5-Carboxy-2-sulfanylpent-2-enoyl-CoA (reacID# r1236)
• 2-Oxoglutaryl-CoA -----> 2-Oxoglutarate (reacID# r1238)
• Thiophene-2-carboxyl-CoA -----> 5-Oxo-4,5-dihydrothiophene-2-carboxyl-CoA (reacID# r1235)
• Thiophene-2-carboxylate -----> 3-Hydroxytetrahydrothiophene-2-carboxylate (reacID# r1283)
• Thiophene-2-carboxylate -----> Tetrahydrothiophene-2-carboxylate (reacID# r1282)
• Thiophene-2-carboxylate -----> Thiophene-2-carboxyl-CoA (reacID# r1234)

• (2Z)-5-Carboxy-2-sulfanylpent-2-enoyl-CoA (compID# c1106)
• 3-Hydroxytetrahydrothiophene-2-carboxylate (compID# c1123)
• 5-Oxo-4,5-dihydrothiophene-2-carboxyl-CoA (compID# c1105)
• 2-Oxoglutarate [328-50-7] (compID# c0880)
• 2-Oxoglutaryl-CoA (compID# c1107)
• Tetrahydrothiophene-2-carboxylate (compID# c1124)
• Thiophene-2-carboxyl-CoA (compID# c1084)
• Thiophene-2-carboxylate [527-72-0] (compID# c1083)

• EC 1.14.99.35 thiophene-2-carboxyl-CoA monooxygenase (enzymeID# e0775)
• EC 3.1.2.- thiolester hydrolase (enzymeID# e0776)
• EC 3.1.2.- 2-oxoglutaryl-CoA thioesterase (enzymeID# e0778)
• EC 3.13.1.- thiol hydrolase (enzymeID# e0777)
• EC 6.2.1.- thiophene-2-carboxylate-CoA ligase (enzymeID# e0774)

Page Author(s): Alex Galaitsis, Tony Dodge and Carla Essenberg
Sun Feb 19 13:51:39 CST 2006 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Thiophene-2-carboxylate Pathway.
It was generated on July 19, 2025 at 9:12:01 PM CDT.

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