The EAWAG-BBD Caffeine Pathway

• Caffeine -----> Paraxanthine (reacID# r1251)
• Caffeine -----> Theobromine (reacID# r1247)
• Caffeine -----> 1,3,7-Trimethyluric acid (reacID# r1321)
• 7-Methylxanthine -----> 7-Methyluric acid (reacID# r1253)
• 7-Methylxanthine -----> Xanthine (reacID# r1249)
• Paraxanthine -----> 1,7-Dimethyluric acid (reacID# r1252)
• Paraxanthine -----> 7-Methylxanthine (reacID# r1257)
• Theobromine -----> 3,7-Dimethyluric acid (reacID# r1250)
• Theobromine -----> 7-Methylxanthine (reacID# r1248)
• 3,6,8-Trimethylallantoin -----> N,N'-Dimethylurea + N-Methylurea + Glyoxylate (reacID# r1323)
• 1,3,7-Trimethyluric acid -----> 3,6,8-Trimethylallantoin (reacID# r1322)

• Caffeine [58-08-2] (compID# c1094)
• N,N'-Dimethylurea [1320-50-9] (compID# c1155)
• 1,7-Dimethyluric acid [33868-03-0] (compID# c1103)
• 3,7-Dimethyluric acid [13087-49-5] (compID# c1101)
• Glyoxylate [298-12-4] (compID# c0014)
• N-Methylurea [598-50-5] (compID# c1176)
• 7-Methyluric acid [612-37-3] (compID# c1104)
• 7-Methylxanthine [552-62-5] (compID# c1098)
• Paraxanthine [611-59-6] (compID# c1102)
• Theobromine [83-67-0] (compID# c1095)
• 3,6,8-Trimethylallantoin [42794-72-9] (compID# c1154)
• 1,3,7-Trimethyluric acid [5415-44-1] (compID# c1153)
• Xanthine [69-89-6] (compID# c1099)

• EC 1.7.3.3 urate oxidase (enzymeID# e0832)
• EC 1.13.12.- theobromine demethylase (enzymeID# e0780)
• EC 1.13.12.- paraxanthine demethylase (enzymeID# e0782)
• EC 1.13.12.- caffeine demethylase (enzymeID# e0779)
• EC 1.14.13.128 heteroxanthine demethylase (enzymeID# e0783)
• EC 1.17.3.2 xanthine oxidase (enzymeID# e0781)
• EC 1.17.5.- caffeine oxidase (enzymeID# e0831)

Page Author(s): Rachael Long, Carla Essenberg, Tony Dodge and Stephan M. Cameron
Mon May 15 09:35:53 CDT 2006 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Caffeine Pathway.
It was generated on July 18, 2025 at 11:40:55 PM CDT.

© 2025, EAWAG.