From 5-Formyl-2-hydroxy-7-methyl-octa-2,4-dienoate to 2-Hydroxy-5-isobutylhexa-2,4-dienoate

Graphic of the reaction.

Medline reference
Kagle J, Porter AW, Murdoch RW, Rivera-Cancel G, Hay AG. Adv Appl Microbiol (2009) 67: 65-108.

Search Medline for ibuprofen bacterial metabolism.
19 citations on March 09, 2012. 
                          5-Formyl-2-hydroxy-7-methyl-octa-2,4-dienoate                          
                                                |
                                                |  H2O
  5-Formyl-2-hydroxy-7-methyl-octa-2,4-dienoate | /
                                  dehydrogenase |/
                                        1.2.1.- |
                                                |\
                                         ExPASy | \
                                                |  3H+ + 2e-
                                                v
                              2-Hydroxy-5-isobutylhexa-2,4-dienoate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Aldehyde -----> Carboxylate (bt0003)
[Ibuprofen] [BBD Main Menu]

Page Author(s): Lynda Ellis and Shawn Balcome
July 15, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1738.
It was generated on January 21, 2025 at 5:46:15 AM CST. 

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