From 2-Hydroxy-cis,cis-muconate semialdehyde to cis-2-Hydroxypenta-2,4-dienoate and Formate

Graphic of the reaction.

Medline reference
Nishino SF, Spain JC. Appl Environ Microbiol (1995) 61(6): 2308-13.

Search Medline for 2-hydroxymuconate semialdehyde hydrolase .
20 citations on March 09, 2012. 
              2-Hydroxy-cis,cis-muconate semialdehyde              
                                 |
                                 |  H2O
  2-hydroxymuconate semialdehyde | /
                       hydrolase |/
                         3.7.1.9 | Search GenBank, 101 hits on Apr. 03, 2012
                           Kyoto |\
                          ExPASy | \
                                 |  H+
                                 v
             cis-2-Hydroxypenta-2,4-dienoate + Formate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)
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Page Author(s): Sujana Mittapalli
August 03, 2010 Contact Us

This is the EAWAG-BBD reaction, reacID# r1671.
It was generated on November 16, 2025 at 4:25:41 PM CST. 

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