From 2,4-Dinitrotoluene to 4-Methyl-5-nitrocatechol

Graphic of the reaction.

Medline reference
Johnson GR, Jain RK, Spain JC. J Bacteriol (2002) 184(15): 4219-32.

Search Medline for 2,4-dinitrotoluene dioxygenase.
12 citations on March 09, 2012. 
            2,4-Dinitrotoluene             
                     |
                     |  NADH + O2
  2,4-dinitrotoluene | /
         dioxygenase |/
           1.14.12.- | Search GenBank, 1 hits on Apr. 03, 2012
                     |\
              ExPASy | \
                     |  NAD+ + NO2-
                     v
         4-Methyl-5-nitrocatechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Nitro-2-unsubstituted aromatic -----> vic-Dihydroxyaromatic (bt0042)
[2,4-Dinitrotoluene] [BBD Main Menu]

Page Author(s): Jeffrey Flynn
April 26, 2008 Contact Us

This is the EAWAG-BBD reaction, reacID# r1501.
It was generated on November 16, 2025 at 9:26:38 AM CST. 

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