From 2,6,7-Trihydroxybenzothiazole to 4-[2-Carboxylatovinyl]-2-hydroxythiazole-5-carboxylate

Graphic of the reaction.

Medline reference
Haroune N, Combourieu B, Besse P, Sancelme M, Reemtsma T, Kloepfer A, Diab A, Knapp JS, Baumberg S, Delort AM. Appl Environ Microbiol (2002) 68(12): 6114-20.

Search Medline for benzothiazole degradation and bacteria.
29 citations on March 09, 2012. 
               2,6,7-Trihydroxybenzothiazole               
                             |
                             |  O2
                    catechol | /
             1,2-dioxygenase |/
                   1.13.11.1 | Search GenBank, 769 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  2H+
                             v
  4-[2-Carboxylatovinyl]-2-hydroxythiazole-5-carboxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxyaromatic -----> intradiol ring cleavage (bt0254)
[2-Mercaptobenzothiazole] [BBD Main Menu]

Page Author(s): Carla Essenberg
August 04, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1295.
It was generated on June 17, 2026 at 8:36:10 PM CDT. 

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