From 4-Fluorobenzoate to 4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate

Graphic of the reaction.

Medline reference
Schreiber A, Hellwig M, Dorn E, Reineke W, Knackmuss HJ. Appl Environ Microbiol (1980) 39(1): 58-67.

Search Medline titles for 4-fluorobenzoate AND bacteria.
5 citations on September 06, 2012. 
                     4-Fluorobenzoate                     
                             |
                             |  NADH + O2 + H+
                    benzoate | /
             1,2-dioxygenase |/
                  1.14.12.10 | Search GenBank, 17 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  NAD+
                             v
  4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[4-Fluorobenzoate (an/aerobic)] [BBD Main Menu]

Page Author(s): Michael Turnbull
April 20, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1205.
It was generated on August 11, 2026 at 9:55:05 PM CDT. 

© 2026, EAWAG.