From 2,4-DNP Hydride Meisenheimer complex to 2,4-Dinitrocyclohexanone

Graphic of the reaction.

Medline reference

Hofmann KW, Knackmuss HJ, Heiss G. Appl Environ Microbiol (2004) 70(5): 2854-60.

Search Medline for Bacterial hydride transferase AND 2,4-Dinitrophenol.

5 citations on March 09, 2012.

    2,4-DNP Hydride Meisenheimer complex     
                      |
                      |   H+ + H-
  hydride transferase | /
                    1 |/
             1.3.99.- | Search GenBank, 7 hits on Apr. 03, 2012
                      v
               ExPASy |
                      |
                      v
[2,4-Dinitrophenol dihydride Meisenheimer complex]
                      |
                      |  2 H+
                      | /
                      |/
                      |
                      |
                      |
                      |
                      v
          2,4-Dinitrocyclohexanone           

EAWAG-BBD Biotransformation rules in accord with this reaction:

2,4-Dinitrophenol hydride complex derivative -----> 2,4-Dinitrocyclohexanone derivative (bt0305)

Page Author(s): Yogesh Kale
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r1068.
It was generated on November 13, 2025 at 3:14:50 PM CST.

© 2025, EAWAG.