From 2,3-Dihydroxy-2-methyl propionate to 2-Hydroxy-2-methyl-1,3-dicarbonate

Graphic of the reaction.

Medline reference
Steffan RJ, McClay K, Vainberg S, Condee CW, Zhang D. Appl Environ Microbiol (1997) 63(11): 4216-22.

Search Medline for 2-Hydroxyisobutyrate AND bacteria.
10 citations on August 16, 2012. 
   2,3-Dihydroxy-2-methyl propionate   
                   |
                   |
                   |
                   |
                   |
                   v\
                   | \
                   |  2H+ + 2e-
                   v
    [2-Formyl-2-hydroxypropionate]     
                   |
                   |  H2O
                   | /
                   |/
                   |
                   |\
                   | \
                   |  3H+ + 2e-
                   v
  2-Hydroxy-2-methyl-1,3-dicarbonate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
primary Alcohol -----> Aldehyde (bt0001)
Aldehyde -----> Carboxylate (bt0003)
[Methyl tert-butyl ether] [BBD Main Menu]

Page Author(s): Charlotte Rosendahl Pedersen
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0620.
It was generated on February 16, 2026 5:38:35 AM CST. 

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