From 2,4,6-Trinitrotoluene to 2-Hydroxylamino-4,6-dinitrotoluene

Graphic of the reaction.

Medline reference
Vorbeck C, Lenke H, Fischer P, Spain JC, Knackmuss HJ. Appl Environ Microbiol (1998) 64(1): 246-252.

Search Medline for nitroreductase AND trinitrotoluene.
40 citations on March 09, 2012. 
         2,4,6-Trinitrotoluene         
                   |
                   |  2NAD(P)H + 2H+
           NAD(P)H | /
    nitroreductase |/
           1.7.1.- | Search GenBank, 256 hits on Apr. 03, 2012
                   |\
            ExPASy | \
                   |  2NAD(P)+ + H2O
                   v
  2-Hydroxylamino-4,6-dinitrotoluene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Nitrobenzenoid -----> Hydroxylaminobenzenoid (bt0078)
[Trinitrotoluene] [2,4,6-Trinitrotoluene (anaerobic)] [BBD Main Menu]

Page Author(s): Sara McFarlan
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0469.
It was generated on December 13, 2025 at 8:14:24 PM CST. 

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