From 4-Hydroxylamino-2,6-dinitrotoluene to 2,4-Dihydroxylamino-6-nitrotoluene

Graphic of the reaction.

Medline reference
Fiorella PD, Spain JC. Appl Environ Microbiol (1997) 63(5): 2007-2015.

Search Medline for nitroreductase AND trinitrotoluene.
40 citations on March 09, 2012. 
  4-Hydroxylamino-2,6-dinitrotoluene   
                   |
                   |  2NADPH + 2H+
      nitrobenzene | /
    nitroreductase |/
           1.7.1.- | Search GenBank, 13 hits on Apr. 03, 2012
                   |\
            ExPASy | \
                   |  2NADP+ + H2O
                   v
  2,4-Dihydroxylamino-6-nitrotoluene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Nitrobenzenoid -----> Hydroxylaminobenzenoid (bt0078)
[Trinitrotoluene] [2,4,6-Trinitrotoluene (anaerobic)] [BBD Main Menu]

Page Author(s): Sara McFarlan
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0466.
It was generated on January 24, 2026 3:45:53 PM CST. 

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