From cis-1,6-Dihydroxy-2,4-cyclohexadiene-1-carboxylic acid to Catechol

Graphic of the reaction.

Medline reference
Jeffrey WH, Cuskey SM, Chapman PJ, Resnick S, Olsen RH. J Bacteriol (1992) 174(15): 4986-96.

Search Medline for bacterial benzoate dihydrodiol dehydrogenase.
7 citations on June 22, 2012. 
  cis-1,6-Dihydroxy-2,4-cyclohexadiene-1-carboxylic acid   
                             |
                             |  NAD+
                    cis-diol | /
               dehydrogenase |/
                    1.3.1.25 | Search GenBank, 31 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  NADH + H+ + CO2
                             v
                         Catechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Carboxy-1,2-dihydroxy-2-hydrobenzenoid -----> Catechol derivative (bt0056)
[Benzoate] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0246.
It was generated on November 12, 2025 at 2:02:45 PM CST. 

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