From 1,2-Dihydroxy-3-methylcyclohexa-3,5-dienecarboxylate to 3-Methylcatechol

Graphic of the reaction.

Medline reference
Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S. Eur J Biochem (1992) 204(1): 113-20.

Search Medline for dihydroxy carboxylate dehydrogenase.
8 citations on March 09, 2012. 
                               1,2-Dihydroxy-3-methylcyclohexa-3,5-dienecarboxylate                                
                                                         |
                                                         |  NAD+
  1,2-dihydroxy-3-methyl-cyclohexa-3,5-diene-carboxylate | /
                                           dehydrogenase |/
                                                 1.3.1.- |
                                                         |\
                                                  ExPASy | \
                                                         |  NADH + H+ + CO2
                                                         v
                                                 3-Methylcatechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Carboxy-1,2-dihydroxy-2-hydrobenzenoid -----> Catechol derivative (bt0056)
[m-Xylene] [BBD Main Menu]

Page Author(s): Brian A. Hyatt and Dong Jun Oh
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0216.
It was generated on November 16, 2025 at 4:19:24 PM CST. 

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