From 3,4-Dihydroxybenzoate to 2-Hydroxy-4-carboxymuconate semialdehyde

Graphic of the reaction.
Medline reference: Noda Y, Nishikawa S, Shiozuka K, Kadokura H, Nakajima H, Yoda K, Katayama Y, Morohoshi N, Haraguchi T, Yamasaki M. J Bacteriol (1990) 172(5): 2704-9.
Search Medline EC codes for 1.13.11.8.: 21 citations on March 09, 2012.

            3,4-Dihydroxybenzoate            
                      |
                      |  O₂
      protocatechuate | /
      4,5-dioxygenase |/
            1.13.11.8 | Search GenBank, 168 hits on Apr. 03, 2012
                Kyoto |
               ExPASy |
                      |
                      v
  2-Hydroxy-4-carboxymuconate semialdehyde

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)

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Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0144.
It was generated on November 7, 2025 at 4:02:07 PM CST.

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