From 3,4-Dihydroxybenzoate to 3-Carboxy-cis,cis-muconate

Graphic of the reaction.

Medline reference
Ohlendorf DH, Lipscomb JD, Weber PC. Nature (1988) 336(6197): 403-5.

Search Medline titles for protocatechuate 3,4-dioxygenase.
75 citations on May 31, 2012. 
        3,4-Dihydroxybenzoate        
                  |
                  |  O2
  protocatechuate | /
  3,4-dioxygenase |/
        1.13.11.3 | Search GenBank, 469 hits on Apr. 03, 2012
            Kyoto |
           ExPASy |
                  |
                  v
     3-Carboxy-cis,cis-muconate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxyaromatic -----> intradiol ring cleavage (bt0254)
[Vanillin] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0143.
It was generated on February 18, 2026 2:43:00 PM CST. 

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